Recommend staying in an apartment rather than a hotel - you really feel like a local. We stayed in one we found on Airbnb - very centrally located and beautifully designed and decorated airbnb.com.au/rooms/8999669
Lots of cool bars and cafes near our location on Herenstraat, and all throughout the Jordaan and Centrum areas.
Lots of quirky one-off designer shops in an area called "9 streets" just south of Jordaan
Highly recommend a visit to the Van Gogh museum - currently there's a brilliant and interesting exhibition comparing his works with Edvard Munch.
Anne Frank Museum is a must - a calm, thought-provoking place.
Make sure you hire bikes - we used Green Bikes but there are plenty of bike hire places.